　　富顿教授（加里·格兰特 Cary Grant 饰）是一位科学家，正在研究一种能够让人返老还童的神奇药物。某一天，富顿用来试验药物的黑猩猩从笼子里逃了出来，在实验室里“大闹天宫”，没想到竟然在误打误撞之下将富顿一直想要研制但始终没有成功的神药给捣鼓了出来。　　对此一无所知的富顿在偶然间喝下了这种药物，很快，药效便发挥了作用，富顿一反常态，言行举止俨然一幅二十岁小伙子的模样。秘书路易斯（玛丽莲·梦露 Marilyn Monroe 饰）前来拜访富顿教授，没想到却被他邀请去游泳、溜冰。之后，富顿的妻子爱德华（金格尔·罗杰斯 Ginger Rogers 饰）亦误食了药物，一连串让人忍俊不禁的趣事就此展开。

失落的世界1960

　　The boisterous, arrogant professor Challenger, a reputed biologist and anthropologist, dares the London Zoological Society to mount an expedition to verify his spectacular claim, without physical proof, that his previous expedition to the Amazonian basin found live dinosaurs. Apart from him and his 'socialite' counterpart, professor Summerlee, it consists of experienced discoverer Lord Roxbury, the young reporter Ed Malone -who got publicly struck down with Challenger's umbrella at his arrival- and Jennifer Holmes, Malone's news agency's boss's daughter, essentially as conditions for putting up the money. In Brazil they are joined by Jennifer's brother David and local 'guide' Manuel Gomez. They soon discover the dinosaurs are real and dangerous, like giant spiders, but loose their helicopter and thus are desperate for a way down from the isolated plateau. They learn Roxbury knew about the fate of Burton White, an explorer whose diary they find, thus presume to be dead, in search of diamonds, and confirmation of the local tribe being the lethal guardians of the plateau's secrets, but also get surprising help...

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